Safron has spent her life steeped in literature, religion and mythology, fields in which she holds her degrees. Her writing and scholarly studies focus on archetypal psychology, astrology, alchemy, goddess traditions, and Greek myth. 

She is a member of the core faculty at Pacifica Graduate Institute, teaching mainly in the Jungian and Archetypal Studies program.

For many years she was the curator of the Joseph Campbell, James Hillman, and Marija Gimbutas manuscript collections at Opus Archives & Research Center.

Safron regularly lectures at Astrology University, the Centre for Astrology, Myth and Symbol (CAMS), and MISPA. Her studies in Jungian and archetypal psychology, myth and alchemy informs her astrological work.  

Safron is author of The Kore Goddess: A Mythology & Psychology (2021), editor of Joseph Campbell's Goddesses: Mysteries of the Feminine Divine (2013), and co-editor of Jung on Astrology (2017). She has published articles in Jungian, archetypal, and astrological journals, and lectures across the US and internationally in Europe, South America and Australia.

Safron and her husband Glen Slater are founders of Winter Press, an imprint of Spring Journal. They also serve on the editorial board of Spring Journal.